Pubrica

Systematic Review Writing & Rewriting Services

Pubrica delivers expert literature synthesis, methodological precision, and publication-ready documentation to enhance the scientific credibility and impact of your research.

Expert Systematic Review Services for Clinical and Evidence-Based Research

PRISMA, Cochrane & PROSPERO-Compliant Reviews for Clinical, Healthcare, and Evidence-Based Research

Crafting a high-quality systematic review that complies with PRISMA guidelines, Cochrane methodology, and PROSPERO registration standards can be challenging, especially for busy researchers and clinicians. At Pubrica, our team of experienced systematic literature review editors, data extractors, and medical and life science PhD writers delivers comprehensive systematic review and meta-analysis services across diverse disciplines, including clinical medicine, public health, nutrition and functional foods, pharma regulatory submissions, AI and machine learning research, and social sciences.

We offer high-quality literature search strategy development, Rayyan/Covidence screenings, data extraction, evidence synthesis, risk of bias measures, and statistical meta-analysis, ensuring methodological rigor, accuracy, and publication-ready quality. Our experts also identify key research gaps, highlighting missing or inadequate evidence to guide clinical decision-making, policy formulation, and future research priorities.

_Systematic Review Services for Clinical and Evidence-Based Research

Why Pubrica

Proven Expertise

Skilled systematic literature review editors, data extractors, and medical/life science PhD writers with experience in PRISMA, Cochrane, and PROSPERO-compliant reviews.

Comprehensive Services

From literature search strategy development and Rayyan/Covidence screening to risk of bias assessment, data extraction, and meta-analysis reporting.

Industry Coverage

Expertise in clinical medicine, public health, nutrition, functional foods, pharma regulatory submissions, AI and machine learning, and environmental risk assessment.

Publication Support

Systematic review manuscript editing, journal formatting, and submission assistance to boost acceptance in high-impact journals

Tailored Solutions

Flexible scope, depth, and budget to match your research needs while maintaining methodological rigor and publication-ready quality.

Types of Systematic Reviews That We Offer

Pubrica provides a comprehensive range of systematic review and evidence synthesis services, tailored to different research goals, study designs, and evidence needs:

What We Do
Scoping Reviews

Identify research gaps and map the breadth of evidence in fields like nutrition and functional foods, public health, AI and machine learning research, and environmental risk assessment.

Systematic Reviews

PRISMA-compliant reviews that answer focused research questions in clinical medicine, epidemiology, social sciences, pharma regulatory submissions, and global health.

Cochrane Systematic Reviews

High-standard reviews for evidence-based medicine, drug efficacy and safety, and healthcare policy formulation, conducted under strict Cochrane methodology.

Mixed Method Systematic Reviews

Combine qualitative and quantitative evidence for complex topics such as behavioural science, education research, and mental health interventions.

Meta-analysis & Network Meta-analysis

Statistical synthesis for clinical trials, nutrition efficacy claims, functional food research, pharmaceutical studies, and public health interventions.

Rapid Reviews / Rapid Evidence Assessments

Provide urgent, high-quality evidence for healthcare policy, public health emergencies, regulatory submissions, and clinical decision-making.

Realist Systematic Reviews

Explore why and how interventions work in health systems research, education policy, social welfare programs, and behavioural interventions.

Umbrella Reviews

Summarize multiple systematic reviews to provide high-level overviews for regulatory agencies, public health organizations, and research consortia.

Qualitative Evidence Synthesis / Meta-synthesis

Integrate qualitative findings in policy and practice research, social work, mental health, and community-based healthcare.

Living Systematic Reviews

Continuously updated reviews for fast-evolving fields like infectious disease management, AI in healthcare, climate change and health, and emerging nutrition science.

Who We Serve

At Pubrica, our systematic literature review and meta-analysis services are trusted by a diverse global clientele. We customize our PRISMA, Cochrane, and PROSPERO-compliant methodology to meet the evidence needs of:

Clinicians & Healthcare Professionals

Evidence synthesis to guide clinical decision-making, guideline development, and best practice recommendations.

Pharmaceutical & Biotech Companies

Pharma regulatory systematic reviews for drug approvals, network meta-analysis for product comparisons, and literature support for post-marketing surveillance.

Health Technology Assessment (HTA) Agencies

Comprehensive reviews assessing clinical effectiveness, cost-effectiveness, and budget impact analysis of interventions and devices.

Policy Makers & Government Bodies

Evidence-based reviews for public health strategies, environmental health policies, and healthcare reforms.

Contract Research Organizations (CROs)

Integrated systematic review writing, data extraction, and evidence synthesis as part of broader clinical research and regulatory services.

Non-Governmental Organizations (NGOs)

Rapid reviews and scoping reviews to support population health studies and global health interventions.

Systematic Reviews by Purpose and Methodological Approach

At Pubrica, we deliver systematic reviews designed to meet diverse research objectives, aligned with PRISMA, Cochrane, JBI, and PROSPERO standards. Our expertise covers both qualitative and quantitative evidence synthesis, ensuring methodological rigor for high-impact publications.

Nutrition & Functional Food Reviews

Assess the efficacy and safety of nutrition interventions and functional ingredients.

Environmental & Occupational Health Reviews

Examine hazards, exposures, and preventive measures.

Economic Evaluation / Cost-effectiveness Reviews

Examine costs, cost-effectiveness, and budget impact in healthcare and public health.

Diagnostic Test Accuracy (DTA) Reviews

Evaluate diagnostic tools using sensitivity, specificity, and predictive value measures.

Living Systematic Reviews

Continuously update findings as new evidence emerges.

Etiology / Risk Reviews

Identify causal relationships and assess risk factors for diseases.

Effectiveness / Intervention Reviews

Assess treatment or intervention outcomes, often with meta-analysis or network meta-analysis to compare interventions.

Psychometric Reviews

Evaluate validity, reliability, and measurement properties of tools.

Methodological Reviews

Assess and improve research methods, designs, and reporting quality.

Prevalence / Incidence Reviews

Summarize disease or condition frequency across populations.

Burden of Disease Reviews

Estimate DALYs, QALYs, and YLL for global and local health priorities.

Health Services & Policy Reviews

Assess healthcare delivery models, access, and system performance.

Genomic & Biomarker Reviews

Evaluate the predictive and diagnostic value of biomarkers.

Adverse Events & Safety Reviews

 Assess treatment or intervention safety profiles.

Pharma Regulatory Submission Reviews
  • Phase I–IV Clinical Trials
  • Pharmacoeconomic Studies
  • Post-Marketing Surveillance (PMS)
  • Real-World Evidence (RWE) Studies
  • Drug Safety & Pharmacovigilance Reports
Infectious Disease Reviews

Synthesize evidence for prevention, treatment, and epidemiology of infectious diseases.

Psychological & Behavioural Reviews

Evaluate mental health, behaviour change, and psychosocial interventions.

Policy Reviews

Summarize evidence for health, environmental, and social policy development.

Rapid Reviews

Deliver timely evidence synthesis for urgent decision-making.

Prognostic Reviews

Predict disease progression, outcomes, or survival rates.

Experiential (Qualitative) Reviews / Meta-synthesis

Use qualitative methods to explore lived experiences, perceptions, and contextual factors.

Mental Health Epidemiology Reviews

 Summarize prevalence, incidence, and risk factors in mental health research.

Speed up your journey of Systematic Review with Pubrica

Gain access to your assistant who will expertly guide you through intricate journal submission processes, shielding you from rejection and ensuring a faster path to getting your work published.

Our Comprehensive Systematic Review Writing & Rewriting Services – Methodology & Support

Pubrica provides end-to-end systematic review writing and rewriting services for researchers and clinicians, ensuring compliance with the PRISMA checklist 2020, Cochrane guidelines, and journal specifications. Our medical and scientific professionals provide publication-ready manuscripts with the most rigorous methodology and evidence, including full project management.

Planning & Protocol Development
Planning & Protocol Development
  • Research Gap & Novelty Analysis – Identify missing or inadequate evidence, assess novelty, and frame clear research objectives.
  • Protocol Writing – Develop systematic review protocols using PICO or SPIDER frameworks to ensure precision and relevance.
  • PROSPERO Registration – Prepare and submit protocols for registration, ensuring transparency and alignment with global reporting standards.
Literature Search & Data Sourcing
Literature Search & Data Sourcing
  • Database Search Strategy Development – Customized keyword combinations, Boolean operators, and filters for targeted searches.
  • Comprehensive Database Coverage – MEDLINE, EMBASE, Cochrane Library, CINAHL, PubMed, CAB Abstracts, BioMed Central, HTSAT, OCLC, Social Service Abstracts, AIDS and Cancer Research, and more.
  • Screening Tools – Covidence, Rayyan, EndNote, Zotero for title/abstract/full-text screening and management.
Data Extraction & Analysis
Data Extraction & Analysis
  • Structured Data Extraction – Use standardized templates for consistent, high-quality data capture.
  • Risk of Bias Assessment – Apply Cochrane Risk of Bias Tool, Newcastle-Ottawa Scale (NOS), or JBI Critical Appraisal Tool; prepare detailed bias tables for appendices.
  • Data Analysis & Synthesis – Quantitative, qualitative, and mixed-method meta-analysis with presentation-ready tables, charts, and figures.
Writing & Formatting
Writing & Formatting
  • Full Manuscript Development – Write the introduction, methodology, results, discussion, and conclusion in compliance with the target journal's
  • Abstract Preparation – Develop PRISMA 2020-compliant abstracts including objectives, methods, results, and conclusions.
  • Referencing & Citation Management – Accurate referencing in APA, AMA, or journal-specific formats.
  • Formatting – Align the manuscript with the target journal’s author guidelines.
Publication Support
Publication Support
  • Journal Selection– Recommend suitable high-impact journals for your topic.
  • Pre-Submission Peer Review – Internal expert review to ensure methodological and editorial readiness.
  • Journal Submission - End-to-End Submission Assistance – From cover letter preparation to follow-up with editorial teams until acceptance.
  • Response to Reviewer comments addressing your submitted systematic review manuscript, resubmission of your manuscript, follow-up with editorial teams, and support up to the point of publication.
Documentation Templates
Documentation Templates

Preparation of essential documentation for keyword search, database utilization (e.g. AIDS and Cancer Research, BioMed Central, CAB Abstracts, Cochrane Library, Cumulative Index to Nursing and Allied Health (CINAHL), Evidence-based medicine, Excerpta Medica (EMBASE), Health Services/ Technology Assessment text (HTSAT), History of Science, Technology and Medicine (OCLC), MEDLINE, Social Service Abstracts (CSA)), setting up inclusion and exclusion criteria, use Boolean Operators, data extraction, assessing the methodological quality and risk of bias to ensure reliability (Cochrane risk of bias tool, Newcastle-Ottawa Scale (NOS), or Jonna Briggs Institute critical appraisal tool), referencing, and formatting, in line with review article journal guidelines.

Enhancement Services
Enhancement Services

Assistance with sourcing of literature, academic research editing review, developing a PRISMA flow diagram to document study selection, and characterizing the evidence to enrich your systematic literature review report. Besides, apart from Excel, we also utilize Covidence, Rayyan, EndNote, or Zotero tools for screening.  

Quality & Integrity Checks
Quality & Integrity Checks
  • Plagiarism & AI Content Analysis – Detailed plagiarism reports ensuring originality and confirming no ChatGPT or AI-generated text.
  • Proofreading & Editing – Language refinement for grammar, clarity, and style.
  • Final Technical Review – Ensure adherence to all PRISMA checklists, methodological requirements, and journal guidelines.
Dedicated Project Coordination
Dedicated Project Coordination

A medical and scientific committed project coordinator to assist with all technical queries related to your scientific report, providing seamless and personalized support. 

How to Get Started with Our Systematic Review

What You Provide What We Provide
Research Questions – Your original idea, hypotheses, or objectives that guide the review. Topic Refinement & Protocol Development – Define objectives using PICO or SPIDER frameworks, prepare detailed methodology, and support PROSPERO registration.
Existing Literature – Instructions on databases to use or existing literature you’ve already collected. MeSH Terms & Keyword Strategy – Develop database search strategies (PubMed, MEDLINE, EMBASE, Cochrane Library, etc.) using Boolean operators.
Scope of Review – Boundaries such as subject areas, timeframe, study types, and demographics. Structured Literature Search & Screening – Title, abstract, and full-text screening using Covidence, Rayyan, EndNote, or Zotero.
Specific Focus Areas – Themes or subtopics for deeper analysis. Data Extraction & Critical Appraisal – Apply standardized templates and conduct risk of bias assessments (Cochrane RoB, NOS, JBI).
Preliminary Findings – Initial patterns observed from existing literature. Data Synthesis & Statistical Analysis – Perform meta-analysis or network meta-analysis; generate summary of findings tables and forest plots.
Data Sources & Databases Used – List of sources for literature collection. PRISMA Flow Diagram & Checklist Compliance – Document study selection and ensure adherence to PRISMA 2020 standards.
Initial Draft of Systematic Review – If available, your first draft for further refinement. Full Manuscript Development – Write IMRAD sections, prepare PRISMA-compliant abstract, and align with target journal format.
Key Theories & Models – Foundational concepts relevant to your research. Identification of Research Gaps & Novelty Check – Highlight missing or inadequate evidence and suggest future research directions.
Quality Checks – Proofreading, plagiarism & AI content analysis, and formatting to target journal guidelines.
Pre-Submission Peer Review – Internal expert review to ensure readiness.
Journal Submission & Editorial Support – Assist with submission, cover letter preparation, reviewer comment addressing, and resubmissions until acceptance.
Our Compliance and Guideline Standards

At Pubrica, we adhere to internationally recognized compliance frameworks and methodological standards to ensure that every systematic review we deliver is credible, reproducible, and transparent. Our process is aligned with:

PRISMA 2020 Statement

Preferred Reporting Items for Systematic Reviews and Meta-Analyses, including the PRISMA Abstract Checklist and flow diagram standards.

Cochrane Handbook for Systematic Reviews

Rigorous methodology for literature search, selection, bias assessment, and synthesis.

PROSPERO Registration

International Prospective Register of Systematic Reviews for protocol transparency.

GRADE

Grading Recommendations Assessment, Development and Evaluation for quality and strength of evidence.

ICMJE

International Committee of Medical Journal Editors’ recommendations for ethical and publication standards.

JBI Critical Appraisal Tools

Joanna Briggs Institute methodology for qualitative, quantitative, and mixed-method reviews.

Newcastle-Ottawa Scale (NOS)

Standardized tool for assessing non-randomized studies in meta-analyses.

AMSTAR 2

Measurement tool to assess the methodological quality of systematic reviews

PICO / SPIDER Frameworks

Structured approach to formulating research questions.

MOOSE Guidelines

Standards for meta-analyses of observational studies in epidemiology.

Risk of Bias Tools

Cochrane RoB tool, ROBINS-I, and other recognized bias assessment frameworks.

PRISMA-ScR

PRISMA extension for scoping reviews.

SRDR (Systematic Review Data Repository)

Used for data storage and transparency in some projects.

Systematic Review Writing & Rewriting Services Sample Work

Download the full Report Now

Explore our systematic review sample work, thoughtfully developed to meet journal-specific formatting requirements, methodological standards (e.g., PRISMA), and submission timelines for successful academic or clinical publication.

Systematic Review Writing and Rewriting Service – Our Packages

At Pubrica, we offer comprehensive and customizable Systematic Review Writing and Rewriting Packages tailored to meet the diverse needs of researchers, academicians, clinicians, and institutions. Our expert team ensures your systematic review is methodologically sound, evidence-driven, and journal-ready.

basic pacakge

Basic

Literature Review Essentials

  • Initial protocol development
  • Database search strategy (2–3 databases)
  • Study selection using PRISMA guidelines
  • Narrative synthesis of findings
s

Standard

Complete Systematic Review

  • Comprehensive protocol development and registration (e.g., PROSPERO)
  • Multi-database search (4–5 databases + grey literature)
  • Risk of bias assessment (e.g., Cochrane RoB, AMSTAR)
  • Data extraction and qualitative/quantitative synthesis
  • Formatting as per target journal guidelines
advanced

Advanced

Publication-Ready & Meta-analysis Support

  • Everything in the Standard Package 
  • Meta-analysis with forest plots and statistical modelling
  • Subgroup and sensitivity analysis 
  • GRADE framework for evidence certainty 
  • Journal selection and submission support 
  • Post-review rewriting based on reviewer comments
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Rewriting & Enhancement

  • Review and critique of an existing systematic review manuscript
  • Structural and methodological enhancements
  • Language editing and reference formatting
  • Rewriting based on reviewer/editor comments
  • Rechecking for plagiarism and grammar

Add-on Services:

  • Network meta-analysis
  • Cost-effectiveness review (for HTA)
  • Scoping review (PRISMA-ScR)
  • Realist review methodology
  • Translation of manuscript for multilingual journals
  • Graphical abstracts & visual summary creation
  • Poster or presentation slide preparation
  • Journal formatting & compliance check
  • Reference management using EndNote, Mendeley, or Zotero

Testimonials

Learn how Pubrica’s systematic review service has empowered researchers to produce high-quality, publication-ready reviews that contribute to evidence-based practice and enhance their academic visibility. Here is what our clients say:

Frequently Asked Questions – Systematic Review Writing & Rewriting Services

 

Yes. We conduct a novelty and gap analysis as part of the topic selection process. Once the topic is defined, we perform a comprehensive literature search across multiple databases.

  • If no similar studies are found, the title is retained.
  • If similar studies exist, we refine the title to address the identified gaps.
  • If an exact match is found, we will propose alternative topics.
    This process is always carried out in consultation with you.

Yes. We offer table and figure formatting as part of our manuscript enhancement services.

  • We first share templates for approval.
  • Once approved, we format and create visualizations.
  • Additional research may be required to complete missing data points.

Yes. You can share your selected papers, and our team will perform data extraction using standardized templates.

  • If you have already identified variables, the process is faster.
  • If not, we can help define them from scratch.
  • Predefined variables serve as a foundation for sourcing, screening, and selecting studies.

Our PRISMA- and Cochrane-compliant process includes:

    • Topic Selection & Protocol Development – Using PICO/SPIDER frameworks; PROSPERO registration optional.
    • Database Search & Article Selection – PubMed, MEDLINE, EMBASE, Cochrane, CINAHL, Scopus, and others; MeSH terms and Boolean operators applied.
    • Screening – Title, abstract, and full-text screening using tools like Covidence or Rayyan.
    • Data Extraction & Risk of Bias Assessment – Cochrane RoB tool, NOS, JBI critical appraisal.
    • Analysis & Visualization – Meta-analysis, forest plots, summary tables.
    • Manuscript Development – IMRAD structure, PRISMA checklist compliance, journal formatting.

We search all relevant open-access and subscription-based databases. If articles require purchase, clients can provide access through their institution or purchase individually. We can guide you on the best access options.

By default, we recommend a comprehensive database search across multiple platforms for rigor and reproducibility. However, if you have specific databases or restrictions, we can adapt our search strategy accordingly.

Yes. Appendices may include search strategies, PRISMA flow diagrams, data extraction tables, and risk of bias summaries. Supplementary material is prepared in line with journal guidelines.

No, Pubrica does not seek authorship. All work is delivered as a confidential, ghostwritten service. You and your co-authors will be the only named authors. We can be acknowledged if you choose.

We offer two free rounds of revisions post-delivery to address feedback and fine-tune the manuscript. Additional rounds can be arranged if required.

Yes. As part of our publication support services, we help interpret reviewer comments, revise the manuscript, prepare rebuttal letters, and resubmit to the journal.

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